Please find enclosed the Call for Papers respective to the Special Issue on
REAL-TIME HEURISTICS AND VIRTUAL SCENARIO SIMULATION IN MEDICINE to be published
by the journal REAL-TIME IMAGING (Academic Press U.K.) in 1996. Please consider
submitting a contribution and helping to disseminate this Call for Papers.
Also, in case you serve on the board of related periodicals, we would like to
ask your kind collaboration toward placing free advertisements in CFP sections.

I thank you in advance for your attention.

With kind regards, 

Roger von Hanwehr
Editorial Board RTI
Washington Radiosurgery Research Institute, Washington D.C. USA; and
Johns Hopkins University, Baltimore, MD, USA

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REAL-TIME IMAGING

----------------------------------------------------------Special Issue on
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          REAL-TIME HEURISTICS AND VIRTUAL SCENARIO SIMULATION IN MEDICINE 

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Guest Editors:

Roger von Hanwehr      Washington Radiosurgery Research Institute, Washington
D.C. USA and
                                  Johns Hopkins University, Baltimore, MD, USA

Charles E. Swenberg    Armed Forces Radiobiology Research Institute, Bethesda,
MD, USA

George F. Popescu      Georgetown University, Washington DC, USA



"Background"

Cross-disciplinary transfer and applied adaption of advanced 'Real-Time'
simulation technologies 
>from the defense and aerospace sectors is increasingly evident in the
progressive migration of scenario simulation capabilities into various
disciplines of applied and theoretical medicine. Iterative simulation and
planning systems for a host of surgical procedures are already in wide clinical
use. Furthermore, selected systems have recently demonstrated implementation of
sophisticated and partially-intelligent semiotic and graphical cue-based
approaches to generate optimization of virtual simulation via systems-induced
operator responses. 

Impending developments in this field now include: 

1)   theoretical methods for optimization using 'solution to an inverse problem'
type models, 

2)   applied multi-dimensional scenario simulation models designed to achieve
optimization              using diverse pattern-recognition methods, 3D neural
net engines, or operator                            feedback-driven heuristic
tools for optimization of constraints, 

3)   stereospatial volume visualization of such optimized data using
multi-layered alpha                     compositing-based and
anatomically-photorealistic rendering routines and, 

4)   advanced 3D projection display systems capable of presenting complex
optimized volume          data patterns in a manner that amplifies signaling
between operator actions and simulator          responses. The impact of 3D
display technologies on quasi-intuitive or heuristic
mechanism-driven system responses and on human operator behavior will assume
major           importance as the complexity of virtual simulated data
environments increases.

Development strategies for evolving medical simulation systems already include:
a) incorporation of 'intelligent' or 'heuristic' mechanisms, b) more effective
coupling of bidirectional operator-systems intercommunication, as well as, c)
promotion of more compliant 'real-time' responses between realworld clinical or
basic science settings and the complex world of virtual simulation. Given these
directions, it is axiomatic that future approaches will include extensive
exploration of  the adaptive challenges increasingly encountered between the
human operator and the 'heuristically-responsive' virtual simulator. 


Special Issue -- "Aims and Scope*: 

A special issue of REAL-TIME IMAGING entitled, "REAL-TIME HEURISTICS AND VIRTUAL
SCENARIO SIMULATION IN MEDICINE", will explore these revolutionary directions in
artificially intelligent heuristics for medical simulation, by examining their
present and potential role in a spectrum of applied clinical uses as well as in
a variety of more theoretical and basic biomedical laboratory and neuroscience
research settings. Applications areas of interest range from simulation for
'live' minimally-invasive neurosurgery, to radiobiologically-optimized inverse
solution treatment simulation for neuroradiosurgery, to pattern
recognition-based modulation of adaptive responses in diagnostic telemedicine,
and to examinations of the cytoskeletal neuronal microenvironment as a learning
and simulation model, to randomly name just a few areas. 

Other Heuristic Scenario Simulation Applications Areas of Interest for this
Special Issue Include (but are not limited to):

----  Real-time automated diagnostic simulation
----  3D multi-modal image hybridization and simulation for metabolic and
functional imaging

----  Computer-guided real-time neruosurgery,
----  Sensor fusion-guided neuronavigation and neuroendoscopy with stereospatial
coordinate-                      		    accurate video to digital
image hybridization and morphing

----  Simulation for orthoprosthetic and bone-remodelling modeling 
----  Simulation for craniofacial and plastics reconstruction

----  Interventional telemedicine and telesurgery

----  LINAC neuroradiosurgery, brachytherapy, and precision stereotactic
radiotherapy
----  Predictive radiation sensitivity/resistance topography mappoing and
radiobiological modeling

----  Simulation for intracellular surgery and radiosurgery models including:
   	      induced rare earth auger and neutron capture processes
	      surgical gene and biovector-based therapies


Submissions  reporting  developments of such issues, of diverse areas of
theoretical or scenario simulation, and focusing on their heuristic and/or
real-time aspects, are welcome. Submissions are not restricted to the specific
applications areas noted above. Prospective authors are invited to submit four
copies of  laser-printed manuscripts written in English to  Alexander Stoyenko
at the address  below before 4 November, 1995. All submissions should conform to
the format adopted by the Real-Time Imaging periodical (Academic Press U.K.).

*Submission deadline*:    4 November 1995

*Address for submission*:

Alexander D. Stoyenko,
Co-Editor-in-Chief,  REAL-TIME IMAGING,  P.O. Box 668
Millwood, New York, 10546 USA
jrti@rtlab12.njit.edu

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INSTRUCTIONS FOR AUTHORS:

Authors should consult INSTRUCTIONS FOR AUTHORS as provided in the periodical,
REAL-TIME IMAGING (Academic Press, U.K.). The journal will use the style
described 
for IEEE transactions.


Special Note for This Issue:

Photographs or CRT Screen Images
One colour illustration per paper is permitted gratis.


Reprints

Authors will receive fifty offprints free of charge.  

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