IEEE SIGNAL PROCESSING MAGAZINE Special Issue on Molecular and Cellular Bioimaging With the advent of a range of new fluorescent probes and other approaches used to tag proteins or other molecules of interest, biologists are now capable of answering previously uncontemplated questions addressing the function of biological systems at all levels, down to molecular and cellular ones. The answers to these questions will come from acquiring and analyzing enormous numbers of digital images using state-of-the-art microscopy techniques in combination with automated, sophisticated and computationally efficient analysis methods. The objective of the special issue is to review and survey research and development in molecular and cellular bioimaging, bringing the vast scope of applications closer to the signal processing community. Tutorial papers are solicited from the following non-exhaustive list of topics. Other related work is also welcome for publication. Suggested Topics: * Modalities: Fluorescence microscopy, electron microscopy, NMR, atomic force microscopy and others. * Labeling approaches, including engineered biosensors for intracellular monitoring. * Acquisition schemes, including multi-probe and time series. * Analysis methods: classification, clustering, tracking, motion analysis, model-based methods and others. * Algorithmic methods: reconstruction, inverse problems, registration, segmentation, restoration and others. Submission Procedure: Prospective authors should submit their responses to the web submission system at, http://www.cspl.umd.edu/spm/, according to the following timetable. White paper due: March 1, 2005 Invitation notification: April 1, 2005 Manuscript due: August 1, 2005 Acceptance Notification: December 1, 2005 Final Manuscript due: January 15, 2006 Publication date: May 2006 Guest Editors: Jelena Kovacevic Center for Bioimage Informatics Depts. of Biomed. Engineering & Electr. and Comp. Engineering Carnegie Mellon University Pittsburgh, PA 15213 jelenak@cmu.edu Robert F. Murphy Center for Bioimage Informatics Depts. of Biological Sciences & Biomed. Engineering Carnegie Mellon University Pittsburgh, PA 15213 murphy@cmu.edu