MICCAI Workshop on Statistical Atlases and Computational Models of the Heart: Imaging and Modelling Challenges http://cilab2.upf.edu/stacom_cesc11/ September 22, 2011, Toronto, Canada Overview: --------- This workshop will follow on from last year’s successful STACOM’10 workshop, which attracted over 50 participants and was published in the Springer LNCS series. This year the workshop will be more focused on validation and benchmarking of cardiac image analysis and simulation tools in order to advance towards their application in clinical environments. Three challenges utilizing data from human, phantom and animal studies will be organized: a segmentation challenge involving patient data from the Cardiac Atlas Project (CAP) led by the University of Auckland; a motion/deformation challenge based on temporal 3D-US and MR images acquired from humans and from a dynamic phantom at King’s College London; and a simulation challenge involving electrophysiological (EP) data acquired in experimental animal studies at Sunnybrook Research Institute, Toronto. These challenges will provide a forum for the discussion of the latest developments in the areas of heart mapping, including atlas construction, statistical modeling of cardiac function across patient groups, cardiac computational physiology, model personalization, ontological schemata for data and results, atlas based functional analysis, and integrated functional/structural analyses, as well as the clinical applicability of these methods. The workshop will be of interest to computer scientists working in imaging and computational modeling, but also to experts in cardiology, radiology, biology and physiology. Through this workshop we would also particularly like to engage a new generation of early career researchers in working at these interfaces. Topics: ------- 1. Efficient and robust statistical representations of cardiac morphology and morphodynamics 2. Quantitative analysis of cardiac images through segmentation and motion/deformation estimation techniques 3. Atlas construction methods. 4. Sharing and reuse of computational cardiac anatomical, mechanical and electrophysiological models 5. Strategies for the personalization of cardiac computational models 6. Parameter sensitivity quantification and identification of relevant parameters in complex computational models 7. Integration of multimodal data in a common reference space 8. Clinical translation of imaging and modelling techniques 9. Statistical analysis of regional heart shape and wall motion characteristics across population groups. 10. Atlas-based physiological analysis of subject-specific characteristics. Challenges: ----------- - Segmentation Challenge: A segmentation challenge will also be included in this workshop, utilizing data from the Cardiac Atlas Project (www.cardiacatlas.org). MRI cine data from up to 300 patients with myocardial infarction will be made available to participants in order to compare automatic segmentation results with a manual ground truth 4D segmentation provided by expert analysts. Participants will submit segmentation results in a standard format, and these will be used to derive consensus segmentations that will be made available in the Cardiac Atlas database for future studies. STAPLE-based techniques will be explored to compare different segmentation results. Points of difference from previous segmentation challenges include the upload of results for development of consensus ground truth for future studies, and time varying analysis including ejection and filling rates. Also, a subset of data with corresponding segmentations will be available from the beginning as a training set. - Motion Tracking Challenge: A motion tracking challenge will also be included in this workshop, using both phantom-based and human kinematic data obtained at University of Ulm and at King’s College London, respectively. A cardiac phantom will be scanned several times to generate a fully controlled set of temporal 3D ultrasound and cine/tagged MR images. In addition, 4D echo and 4D cine/tagged MRI will also be available for a set of human volunteers. Subsequently, both types of data will be processed to generate ground-truth to compare with the different motion estimation techniques. The comparisons will also be made on other indexes, like the resulting regional strain. - EP Simulation Challenge: An EP simulation challenge will be included in this workshop. The goal of this challenge is to compare strategies for the customization of realistic cardiac computational models using in-vivo experimental data. Two complete datasets obtained in a porcine model: one healthy heart and one heart with chronic infarct (obtained at Sunnybrook Research Institute, Toronto) will be provided in advance, such that all submissions can use it. These datasets will contain 3D cardiac geometry, scar and fiber orientations from high-resolution DT-MRI, as well as endocardial and epicardial CARTO electro-anatomical maps. The EP maps were acquired in-vivo, in sinus rhythm. Participants will submit results of their customized models (for instance, they can include simulation of Purkinje activation, analysis of EP signals, model parameterization, etc), in order to allow discussions on different model customization and parametrization strategies that could be of interest in future clinical applications. Dates: ------ 15 June 2011 --- Paper pre-registration (title and authors) on the submission system 30 June 2011 --- Paper submission deadline 20 July 2011 --- Notification of acceptance 1 August 2011 --- Camera-ready submission deadline 5 August 2011 --- Final acceptance notification Organizers: ----------- Oscar Camara (Universitat Pompeu Fabra, ES) Ender Konukoglu (Microsoft Research, UK) Mihaela Pop (University of Toronto, CA) Kawal Rhode (King’s College London, UK) Maxime Sermesant (INRIA, FR) Alistair Young (University of Auckland, NZ) Contact: -------- pc-stacom2011@inria.fr Submissions: ------------ Authors are invited to submit articles with a limit of 8 pages. The format should follow the LNCS style following the MICCAI main conference guidelines. A double-blind review process will be applied judging submissions for originality, relevancy and significance. The paper submission system will open after June 10, 2011.